刘镕
刘镕

1、职称职务:讲师刘镕照片

2、学科专业:组织学与胚胎学

3、研究方向:发育生物学

4、联系电话:15623215710

5、Email:liurong19840901@whu.edu.cn

6、教育经历:

2008/09–2013/06,武汉大学,基础医学院,博士(硕博连读)

2003/09–2008/06,武汉大学,公共卫生学院(现健康学院),学士

7、工作经历

2015/07–至今,武汉大学,基础医学院,讲师

2013/07–2015/06,北京大学,公共卫生学院, 博士后

8、留学经历

2019/10-2021/06,美国宾夕法尼亚大学(University of Pennsylvania),Visiting Scholar

2012/10-2012/12,德国吉森大学(Justus Liebig University Giessen),Visiting Ph.D.

9、目前主要科学研究领域和兴趣:

   发育生物学;生殖发育与减数分裂

10、教学情况:

参与临床医学、口腔医学、检验医学、公卫与护理医学专业等本科生的《组织学与胚胎学》、《组织与功能》、《人体结构学》、《基础医学综合实验》、《病原生物学》以及《人体寄生虫学》课程的理论和实践教学;

参与全校本科生通识课程《旅行生活与寄生虫病》、《食源性寄生虫病》、《现代生活方式与寄生虫感染》的实践教学;

参与研究生的《现代组织学技术》、《医学基础研究技术》、《科学研究方法与规范》、《临床微生物学》和《病原生物学》的理论与实验教学;

参与MBBS专业留学生《Histology and Embryology》课程的实践课程。

11、主持及参与的科研项目:

(1) 湖北省自然科学基金面上项目,项目编号:2017CFB239,microRNAs在日本血吸虫生长发育调控中的作用机制研究,2017/01-2018/12,5万,主持

(2) 武汉大学自主科研项目-青年教师资助项目,项目编号:2042017kf0033,利用代谢组学方法筛选宿主免疫系统调节日本血吸虫生长发育的关键分子及其机制研究,2017/01-2018/12,15万,主持

(3) 湖北省卫生计生委血防专项,项目编号:WJ2017X002,基于比较转录组学的利用免疫缺陷小鼠感染模型筛选调控日本血吸虫生长发育的免疫相关基因的研究,2017/01-2019/01,2万,主持

(4) 国家重点研发计划“生殖健康及重大出生缺陷防控研究”重点专项,项目编号:SQ2018YFC100266,生殖细胞染色体行为的分子调控,2018/12-2021/12,3099万,参与

12、近期代表性论文(*通讯作者,#并列一作):

(1) Wen-Jun Cheng, Meng-Jie Gu, Feng Ye, Yao-Dan Zhang, Qin-Ping Zhong, Hui-Fen Dong, Rong Liu*, Hong Jiang*. Prohibitin 1 (PHB1) controls growth and development and regulates proliferation and apoptosis in Schistosoma japonicum. FASEB Journal, 2020 Jul 6. doi:10.1096/fj.201902787RRR.

(2) Yang Xu#, Rong Liu#, N Adrian Leu, Lei Zhang, Ilsiya Ibragmova, David C Schultz, P Jeremy Wang*. A cell-based high-content screen identifies isocotoin as a small molecule inhibitor of the meiosis-specific MEIOB-SPATA22 complex. Biol Reprod. 2020; ioaa062. doi:10.1093/biolre/ioaa062

(3) Rong Liu*, Wen-Jun Cheng, Feng Ye, Yao-Dan Zhang, Qin-Ping Zhong, Hui-Fen Dong, Hong-Bin Tang, Hong Jiang*. Comparative Transcriptome Analyses of Schistosoma japonicum Derived From SCID Mice and BALB/c Mice: Clues to the Abnormality in Parasite Growth and Development. Frontiers in Microbiology, 2020, 11: 274. doi: 10.3389/fmicb.2020.00274.

(4) Rong Liu, Feng Ye, Qinping Zhong, Shuhong Wang, Ting Chai, Huifen Dong, Zhenping Ming*. Comparative serum metabolomics between SCID mice and BALB/c mice with or without Schistosoma japonicum infection: insights into the abnormal growth and development of schistosome in SCID mice. Acta Tropica. 2019, 200: 105186. doi: 10.1016/j.actatropica.2019.105186.

(5) Wen-Jun Cheng, Hong Jiang, Hui-Fen Dong, Rong Liu*. Advances in researches of exosomes and other extracellular vesicles in parasites and parasitic diseases. Chinese journal of schistosomiasis control. Chinese journal of schistosomiasis control. 2019, 31(5): 555-559.

(6) Rong Liu, Wen-Jun Cheng, Hong-Bin Tang, Qin-Ping Zhong, Zhen-Ping Ming, Hui-Fen Dong*. Comparative metabonomic investigations of Schistosoma japonicum from SCID mice and BALB/c mice: clues to developmental abnormality of schistosome in the immunodeficient host. Frontiers in Microbiology, 2019, 10: 440. doi: 10.3389/fmicb.2019.00440.

(7) Feng Ye, Hui-Fen Dong, Rong Liu*. Comparison of methods for exosomes isolation. Chinese journal of pathogenic biology. 2019, 14(1): 118-122.

(8) Shou-jia Xiong, Rong Liu, Qin-Ping Zhong, Hong-ying Zong, Wan-hong Yao, Hui-Fen Dong*. Investigation on intestinal nematode infections and their risk factors in Shanpo Sub-district, Jiangxia District, Wuhan City. Chinese journal of schistosomiasis control. 2018, 30(5): 567-570, 580.

(9) Tao Xiong, Qin-ping Zhao, Rong Liu, Ming-sen Jiang, Hui-fen Dong*. Enzymology of snails under treatment of molluscicides. Chinese journal of schistosomiasis control. 2018, 30(2): 237-240, 243.

(10) Xiao-Kun Li#, Qing-Bin Lu#, Wei-Wei Chen#, Wen Xu#, Rong Liu, Shao-Fei Zhang, Juan Du, Hao Li, Ke Yao, Di Zhai, Pan-He Zhang, Bo Xing, Ning Cui, Zhen-Dong Yang, Chun Yuan, Xiao-Ai Zhang, Zhe Xu, Wu-Chun Cao*, Zeping Hu*, Wei Liu*. Arginine deficiency is involved in thrombocytopenia and immunosuppression in severe fever with thrombocytopenia syndrome. Sci Transl Med. 2018 Sep 19;10(459). pii: eaat4162.

(11) Yan-wei Li, He-hua Hu, Zheng-wen He, Zhao-gang Xu, Chun-bin Zhang, Xiao-shan Zhou, Yao Li, Rong Liu, Hui-fen Dong, Qin-ping Zhao*. Survey of knowledge and practice of residents about schistosomiasis prevention and control in endemic areas of Jingzhou City. Chinese journal of schistosomiasis control. 2017, 30(1): 57-61.

(12) Yan Ru Gao, Wen Ling Huang, Chun Lian Tang, Rong Liu, Qin Ping Zhao, Zhen Ping Ming, Hui Fen Dong*. Influence of Schistosoma japonicum programmed cell death protein 10 on the growth and development of schistosomula. Parasit Vectors. 2018, 11(1): 46.

(13) Yanru Gao, Xiaoshan Zhou, Huan Wang, Rong Liu, Qing Ye, Qinping Zhao, Zhenping Ming, Huifen Dong*. Immunization with recombinant schistosome adenylate kinase 1 partially protects mice against Schistosoma japonicum infection. Parasitol Res. 2017, 116(6): 1665-1674.

 (14) Tao Xiong, Qin Ping Zhao, Xing Jian Xu, Rong Liu, Ming Sen Jiang*, Hui Fen Dong*. Morphological and enzymatical observations in Oncomelania hupensis after molluscicide treatment: implication for future molluscicide development. Parasitol Res. 2016 Nov; 115(11): 4139-4152.