SCI收录论文（近五年）
1. Li J#, Luo H W#, He Z, Zhang L, Guo Y, Ma L, Magdalou J, Chen LB, Wang H*. Gender-specific increase in susceptibility to metabolic syndrome of offspring rats after prenatal caffeine exposure with post-weaning high-fat diet. Toxicol Appl Pharmacol, 2015; 284:345-53
2. Xu D#, Bai J#, Zhang L, Shen L, Wang LL, Liu ZF, Xia LP, Wang H*. Prenatal nicotine exposure-induced intrauterine programming alteration increases the susceptibility of high-fat diet-induced non-alcoholic simple fatty liver in female adult offspring rats. Toxicol Res 2015; 4 (1):112-20.
3. Wu DM#, He Z#, Ma LP, Wang LL, Ping J*, Wang H. Increased DNA methylation of scavenger receptor class B type I contributes to inhibitory effects of prenatal caffeine ingestion on cholesterol uptake and steroidogenesis in fetal adrenals. Toxicol Appl Pharmacol. 2015;285(2):89-97.
4. Zhaojing Wang, Yonghong Xu, Xiangning Meng, Fumio Watari, Hudan Liu*, Xiao Chen *, Suppression of c-Myc is involved in multi-walled carbon nanotubes' down-regulation of ATP-binding cassette transporters in human colon adenocarcinoma cells. Toxicol Appl Pharm. 2015; 282(1):42-51.
5. Wen YX, Li J, Wang LL, Tie K, Magdalou J, Wang H*, Chen LB*. UDP-glucose dehydrogenase modulates proteoglycan synthesis in articular chondrocytes: its possible involvement and regulation in osteoarthritis. Arthritis Research & Therapy 2014; 16(6):484.
6. Zhang C#, Xu D#, Luo HW, Lu J, Liu L, Ping J, Wang H*. Prenatal xenobiotic exposure and intrauterine hypothalamus-pituitary-adrenal axis programming alteration. Toxicology. 2014;325C:74-84.
7. Feng JH*#, Yan YE, Liang G, Liu YS, Li XJ, Zhang B J, Chen LB, Yu H, He XH, Wang H*. Maternal and fetal metabonomic alterations in prenatal nicotine exposure-induced rat intrauterine growth retardation. Mol Cell Endocrinol. Accepted. Mol Cell Endocrinol 2014;394(1-2):59-69.
8. Ping J#, Wang JF#, Liu L, Yan YE, Liu F, Lei YY, Wang H*. Prenatal caffeine ingestion induces aberrant DNA methylation andhistone acetylation of steroidogenic factor 1 and inhibits fetaladrenal steroidogenesis. Toxicology 2014;321:53-61.
9. Yan YE#, Liu L#, Wang JF, Liu F, Li XH, Qin HQ, Wang H*. Prenatal nicotinic exposure suppresses fetal adrenal steroidogenesis via steroidogenic factor 1 (SF-1) deacetylation. Toxicol Appl Pharmacol., 2014;277:231-41.
10. Xia LP#, Shen L#, Kou H, Zhang BJ, Zhang L, Wu Y, Li XJ, Xiong J, Yu Y, Wang H*. Prenatal ethanol exposure enhance the susceptibility to metabolic syndrome in offspring rats by HPA axis-associated neuroendocrine metabolic programming. Toxicol lett. 2014;226:98-105.
11. Kou H#, Liu Y#, Liang G, Huang J, Hu J, Yan YE, Li X, Yu H, He X, Zhang B, Zhang Y, Feng J, Wang H*. Maternal glucocorticoid elevation and associated blood metabonome changes might be involved in metabolic programming of intrauterine growth retardation in rats exposed to caffeine prenatally. Toxicol Appl Pharmacol. 2014;275(2):79-87.
12. Luo H, Deng Z, Liu L, Shen L, Kou H, He Z, Ping J, Xu D, Ma L, Chen L, Wang H*. Prenatal caffeine ingestion induces transgenerational neuroendocrine metabolic programming alteration in second generation. Toxicol Appl Pharmacol. 2014;274(3)383-92.
13. Shen L, Liu ZF, Gong J, Zhang L, Wang LL, Magdalou J, Chen LB, Wang H*. Prenatal ethanol exposure programs an increased susceptibility of non-alcoholic fatty liver disease in female adult offspring rats. Toxicol Appl Pharmacol, 2014;274(2)263-73.
14. Wang LL#, Shen L#, Ping J, Zhang L, Liu ZF, Wu Y, Liu YS, Huang HG, Chen LB, Wang H*. Intrauterine metabolic programming alteration increased susceptibility to non-alcoholic adult fatty liver disease in prenatal caffeine-exposed rat offspring. Toxicol lett. 2014;224(3):311-8.
15. L. Zhao, Y. Xu, H. Qin, S. Abe, T. Akasaka, T. Chano, F. Watari, T. Kimura, N. Komatsu*, X. Chen *. Platinum on Nanodiamond: A Promising Prodrug Conjugated with Stealth Polyglycerol, Targeting peptide, and Acid-Responsive Antitumor Drug. Adv Funct Mater. 2014; 24(34): 5348–5357.
16. L. Zhao, Y. Xu, S. Abe, T. Akasaka, T. Watari, T. Kimura, N. Komatsu, X. Chen *. Polyglycerol-coated nanodiamond as a macrophage-evading platform for selective drug delivery in cancer cells. Biomaterials. 2014; 35(20): 5393–5406.
17. Guo Y#, Ma Z#, Kou H, Sun R, Yang H, Smith CV, Zheng J*, Wang H*. Synergistic effects of pyrrolizidine alkaloids and lipopolysaccharide on preterm delivery and intrauterine fetal death in mice. Toxicol Lett. 2013;221:212-8
18. Xu D#, Xia LP#, Shen L, Lei YY, Liu L, Zhang L, Magdalou J, Wang H*. Prenatal nicotine exposure enhances the susceptibility to metabolic syndrome in adult offspring rats fed high-fat diet viaalteration of HPA axis-associated neuroendocrine metabolic programming. Acta Pharmacol Sin. 2013;34:1526-34.
19. Zhang L#, Xu D#, Zhang B, Liu Y, Chu F, Guo Y, Gong J, Zheng X, Chen L, Wang H*. Prenatal food restriction induces a hypothalamic-pituitary-adrenocortical axis-associated neuroendocrine metabolic programmed alteration in adult offspring rats. Arch Med Res 2013;44:335-45.
20. Shang YZ, Zhang H, Cheng JJ, Miao H. Liu YP, Cao K, Miao H, Wang H*. Falvonoid from Scutellaria baicalensis Georgi are effective to treat cerebral ischemia/reperfusion. Neural Regeneration Research 2013;8:514-22.
21. Li Y#, Zhao H, Wang Y, Zheng H, Yu W, Chai H, Zhang J, Falck JR, Guo AM, Yue J, Peng R, Yang J*. Isoliquiritigenin induces growth inhibition and apoptosis through downregulating arachidonic acid metabolic network and the deactivation of PI3K/Akt in human breast cancer. Toxicol Appl Pharmacol. 2013;272:37-48.
22. Deng Y, Cao H, Cu F, Xu D, Lei YY, Tan Y, Magdalou J, Wang H, Chen LB*. Nicotine-induced retardation of chondrogenesis through down-regulation of IGF-1 signaling pathway to inhibit matrix synthesis of growth plate chondrocytes in fetal rats. Toxicol Appl Pharmacol 2013;269:25-33.
23. Luo GC, Kong XC, Lu LN, Xu XH, Wang H, Ma XS*. Glucagon-like peptide 1 potentiates glucotoxicity-diminished insulin secretion via stimulation of cAMP-PKA signaling in INS-1E cells and mouse islets. International J Biochem Cell Biol 2013;45:483-90.
24. Cheng Y, X. Chen *, Song W, Kong Z, Li P, Liu Y. Contribution of silver ions to the inhibition of infectivity of Schistosoma japonicum cercariae caused by silver nanoparticles. Parasitology. 2013; 140(5):617-625.
25. Xiong J, Guo Y, Li LY, Hu H, Qu XL, Sun XZ, Liu SH, Wang H*. A Herbal Composition of Semen Hoveniae, Radix Puerariae, and Fructus Schisandrae Shows Potent Protective Effects on Acute Alcoholic Intoxication in Rodent Models. Evidence-Based Complementary and Alternative Medicine. 2012;2012:638197
26. Qin J, Shang L, Ping AS, Li XJ, Yu H, Magdalou J, Chen LB, Wang H*. TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1beta-induced rat osteoarthritis chondrocytes in vitro. Arthritis Research & Therapy. 2012;14(6):R242
27. Xu D, Wu Y, Liu F, Liu YS, Shen L, Lei YY, Liu J, Ping J, Qin J, Zhang C, Chen LB, Magdalou J, Wang H*. A hypothalamic–pituitary–adrenal axis-associated neuroendocrine metabolic programmed alteration in offspring rats of IUGR induced by prenatal caffeine ingestion. Toxicol Appl Pharmacol. 2012;264(3):395-403
28. Liu YS, Xu D, Feng JH, Kou H, Liang G, Yu H, He XH, Zhang BF, Chen LB, Magdaloue J, Wang H*. Fetal rat metabonome alteration by prenatal caffeine ingestion probably due to the increased circulatory glucocorticoid level and altered peripheral glucose and lipid metabolic pathways. Toxicol Appl Pharmacol. 2012;262:205-16
29. Xu D, Zhang BJ, Liang G, Ping J, Kou H, Li XJ, Xiong J, Chen LB, Magdalou J, Wang H*. Caffeine-induced Activated glucocorticoid metabolism in hippocampus causes hypothalamic-pituitary-adrenal axis inhibition in fetal rats. Plos One. 2012;7(9):e44497
30. Guo Y*, Zhu LR, Lu G, Wang H, Hong JY. Selective Expression of CYP2A13 in Human Pancreatic Islet Cells. Drug Metab Dispo 2012;10:1878-82
31. Xu D, Liang G, Yan YE, He WW, Liu YS, Chen LB, Magdalou J, Wang H*. Nicotine-induced over-exposure to maternal glucocorticoid and activated glucocorticoid metabolism causes hypothalamic–pituitary–adrenal axis-associated neuroendocrine metabolic alterations in fetal rats.Toxicol Lett. 2012;209:282-90
32. Liu L, Liu F, Kou H, Zhang BJ, Xu D, Chen B, Chen LB, Magdalou J, Wang H*. Prenatal nicotine exposure induced a hypothalamic-pituitary-adrenal axis-associated neuroendocrine metabolic programmed alteration in intrauterine growth retardation offspring rats. Toxicol Lett.2012 ;214:307-13
33. Ping J*, Lei Y, Liu L, Wang TT, Feng YH, Wang H*. Inheritable stimulatory effects of caffeine on steroidogenic acute regulatory protein expression and cortisol production in human adrenocortical cells. Chemico-Biological Interactions. 2012;195:68-75
34. Yu W, Chai HY, Li Y, Zhao HX, Xie XF, Zheng H, Wang CL, Wang X, Yang GF, Cai XJ, Falck JR, Yang J*. Increased expression of CYP4Z1 promotes tumor angiogenesis and growth in human breast cancer. Toxicol Appl Pharm. 2012;264(1):73-83
35. Zhao HX, Li Y, Wang YZ, Zhang J, Ouyang XM, Peng RX, Yang J*. Antitumor and immunostimulatory activity of a polysaccharide–protein complex from Scolopendra subspinipes mutilans L. Koch in tumor-bearing mice. Food Chem Toxicol. 2012;50(8):2648-55
36. Zhong YY, Dong GC, Luo HG, Cao J, Wang C, Wu JY, Feng YQ, Yue J*. Induction of brain CYP2E1 by chronic ethanol treatment and related oxidative stress in hippocampus, cerebellum, and brainstem. Toxicology. 2012;302(2-3):275-84
37. Tian T, Li J, Wang MY, Xie XF, Li QX*. Protective effect of 20-hydroxyeicosatetraenoic acid (20-HETE) on adriamycin-induced toxicity of human renal tubular epithelial cell (HK-2).Euro J Pharmacol.2012;683:246-51
38. Huang J, Zhou S, Ping J, Pan XL, Liang G, Xu D, Kou H, Bao C, Wang H*. Role of p53-dependent placental apoptosis in the reproductive and developmental toxicities of caffeine in rodents. Clin Exp Pharmacol Physiol. 2012;39:357-63
39. Guo Y，Wu XQ, Zhang C, Liao ZX, Wu Y, Wang H*. Protective effect of sodium ferulate on acetaldehyde-treated precision-cut rat liver slices. J Med Food. 2012;15:557-62
40. Zhang XY, Zhou W, Xu H, Zhang YX, Yang J*, Duan GL. LC–ESI/MS Analysis of Levodopa and Methyldopa (IS) in Beagle Dog Pharmacokinetic Study after Oral Administration and Domperidone Given in Advance. J Chin Chem Soc. 2012;59:710-7
41. Zhang XY, Zhou W, Yang J*, Duan GL. Pharmacokinetic Study on Levodopa and Benserazide Hydrochloride Tablets in Beagle Dogs by HPLC-ESI-MS/MS. Lat Am J Pharm. 2012;31(9):1238-46
42. Song YJ，Li J，Xie XF，Wang H，Li QX*. Effects of amlodipine on TGF-b-induced Smad2, 4 expressions in adriamycin toxicity of rat mesangial cells. Archives of Toxicology. 2011，85:663-668.
43. Wang TT, Chen M, Liu L, Cheng HY, Yan YE, Feng YH, Wang H*. Nicotine induced CpG methylation of Pax6 binding motif in StAR promoter reduces the gene expression and cortisol production. Toxicol Appl Pharmacol. 2011;257:328-37.
44. Ping J*, Lei Y, Liu L, Wang TT, Feng YH, Wang H*. Inheritable stimulatory effects of caffeine on steroidogenic acute regulatory protein expression and cortisol production in human Adrenocortical Cells. Chemico-Biological Interactions. 2012;195:68-75.
45. Yu W, Chen L, Yang YQ, Falck JR, Guo AM, Ying L, Yang J*. Cytochrome P450 omega-hydroxylase promotes angiogenesis and metastasis by upregulation of VEGF and MMP-9 in non-small cell lung cancer. Cancer Chemotherapy and Pharmacology. 2011;68(3):619-29.
46. Ping J, Li JT, Liao ZX, Shang L, Ao Y, Wang H*. Indole-3-carbinol inhibits hepatic stellate cells proliferation by blocking NADPH oxidase/reactive oxygen species/p38 MAPK pathway. Euro J Pharmacol. 2011;650(2-3):656-62.
47. Xue Y, Tie CR, Li J, Tian T, Li QX*. Ligustrazine inhibits lipopolysaccharide-induced proliferation by affecting P27, Bcl-2 expression in rat mesangial cells. European Journal of Pharmacology. 2011, 665:8-12.
48. Liang G, Chen M, Pan XL, Zheng J, Wang H*. Ethanol-induced inhibition of fetal hypothalamic-pituitary-adrenal axis due to prenatal overexposure to maternal glucocorticoid in mice. Exp Toxic Pathol. 2011;63:607-11.
49. Xu D, Chen M, Pan XL, Xia LP, Wang H*. Dexamethasone induces fetal developmental toxicity through affecting the placental glucocorticoid barrier and depressing fetal adrenal function. Environ Toxicol Pharmacol. 2011;32:356-63.
50. Li Y, Yan YY, Wang H*. Enhancement of placental antioxidative function and P-gp expression by sodium ferulate mediated its protective effect on rat IUGR induced by prenatal tobacco/alcohol exposure. Environ Toxicol Pharmacol. 2011;32:465-71.
51. Guo Y, Wu XQ, Zhang C, Liao ZX, Wu Y, Xia ZY, Wang H*. Effect of indole-3-carbinol on ethanol-induced liver injury and acetaldehyde-stimulated HSC activation using precision-cut rat liver slices. Clin Exp Pharmacol Physiol. 2010;37(12):1107-13.
52. Xu D, Chen M, Guo Y, Liang G, Zhang BJ, Tan J, Magdalou J, Wang H*. Synergistic antifibrotic effect of verapamil and interferon-gamma in rats:partially based on enhanced verapamil oral bioavailability. Eur J Gastroenterol Hepatol. 2010;22(4):466-73.
53. Wang H*, Xu D，Chen M，Peng RX，Yue J. Testosterone-metabolizing capacity and characteristics of adrenal microsomes in human fetus in vitro. J Pediatr Endocrinol Metab. 2010;23(1):143-51.
54. Xu Y, X. Chen *, Cheng Y, Xing Y. Multiwalled carbon nanotubes inhibit fluorescein extrusion and reduce plasma membrane potential in in vitro human glioma cells. J Biomed Nanotechnol. 2010;6(3):260-71.
55. X. Chen *, H. Schluesener. Multi-walled carbon nanotubes affect drug transport across cell membrane in rat astrocytes. Nanotechnology. 2010;21(10):105104.