1、职称职务：教授，博导，基础医学院副院长

2、学科专业：生物医学工程

3、研究方向：生物材料与再生医学

4、实验室位置：1号楼3楼307室

5、Email：yunchen@whu.edu.cn

6、学习经历：

1987.9-1991.7 西南师范大学化学系，学士

1991.9-1994.6 湖北省化学研究所，硕士

2001.9-2004.6 武汉大学化学与分子科学学院，博士

7、主要工作经历与任职：

1994.7-2000.7  湖北医科大学实验检测中心 助教/讲师

2000.8-2006.10 武汉大学医学结构生物学研究中心 讲师/副教授

2006.11-至今  武汉大学医学结构生物学研究中心/武汉大学基础医学院生物医学工程系 教授、博士生导师

其中，2006.11-2008.10  Saskatoon Research Centre, Agriculture and Agri-Food Canada, Canada. 博士后

8、目前主要科学研究领域和兴趣：

主要从事生物材料与再生医学研究，重点研究大豆蛋白质、纤维素、壳聚糖、淀粉等天然高分子及其改性材料在神经组织工程、皮肤组织工程和骨组织工程领域中的应用。已主持国家自然科学基金、国家留学基金委国外合作项目、湖北省自然科学基金、湖北省卫生厅科技人才基金、湖北省自然科学基金计划青年杰出人才等项目多项，合作参与国家863计划、国家自然科学基金重点项目等多项课题研究。发表SCI收录论文近100篇。主编专著2部、教材1部，参编教材、专著4部；授权专利10项。

9、主要学术兼职：

湖北省生物医学工程学会理事；湖北省电镜学会会员；中国生物医学工程学会会员；中国生物材料学会会员。

10、教学情况：

承担研究生《生物医学研究方法与前沿技术》、《纳米医学》和本科生《现代生物医学技术前沿》、《高分子科学导论》、《再生医学》等课程的教学。

11、获奖及荣誉：

湖北省卫生厅科技人才项目获得者；湖北省自然科学基金计划青年杰出人才项目获得者；2016年度武汉大学朱裕璧医学奖获得者

12、近五年主要代表性论文：

[1] Zijian Wang#, Weikang Hu#, Wenjie You#, Gang Huang, Weiqun Tian, Céline Huselstein, Chin-Lee Wu, Yu Xiao, Yun Chen*, Xinghuan Wang*. Antibacterial and angiogenic wound dressings for chronic persistent skin injury. Chemical Engineering Journal. 2021, 404, 126525. 

[2] Yanan Zhao, Utkan Demirci*, Yun Chen*, Pu Chen*. Multiscale brain research on a microfluidic chip. Lab on a Chip. 2020, 1531-1543.

[3] Qiang Zhang#, Zan Tong#, Feixiang Chen, Xiaomei Wang, Mingxin Ren, Yanan Zhao, Ping Wu, Xiaohua He, Pu Chen*, Yun Chen*. Aligned soy protein isolate-modified poly(L-lactic acid) nanofibrous conduits enhanced peripheral nerve regeneration multiscale brain research on a microfluidic chip. Journal of Neural Engineering. 2020, 17, 036003.

[4] Yanan Zhao#, Ao Xiao#, Ping Wu, Feixiang Chen, Qiang Zhang, Xiao Liang, Xinwei Han, Xiaowen Shi, Yinping Li*, Yun Chen*. Fabrication of hydroxypropyl chitosan/soy protein isolate hydrogel for effective hemorrhage control. Tissue Engineering Part A. 2020, DOI: 10.1089/ten.TEA.2020.0174.

[5] Feixiang Chen, Qiang Zhang, Ping Wu, Yanan Zhao, Xiaotong Suo, Ao Xiao, Meifang Ke, Xiaohua He, Zan Tong and Yun Chen*. Green fabrication of seedbed-like flammulina velutipes polysaccharides–derived scaffolds accelerating full-thickness skin wound healing accompanied by hair follicle regeneration. International Journal of Biological Macromolecules. 2021, 167, 117-129. 

[6] Minhao Wu#, Ping Wu#, Lingfei Xiao, Yanteng Zhao, Feifei Yan, Xing Liu, Yuanlong Xie, Chong Zhang, Yun Chen*, Lin Cai*. Biomimetic mineralization of novel hydroxyethyl cellulose/soy protein isolate scaffolds promote bone regeneration in vitro and in vivo.  International Journal of Biological Macromolecules. 2020, 162, 1627-1641.

[7] Ping Wu#, Yanan Zhao#, Feixiang Chen, Ao Xiao, Qiaoyue Du, Qi Dong, Meifang Ke, Xiao Liang, Qing Zhou*, Yun Chen*. Conductive hydroxyethyl cellulose/soy protein isolate/polyaniline conduits for enhancing peripheral nerve regeneration via electrical stimulation. Frontiers in Bioengineering and Biotechnology. 2020, 8, 709. 

[8] Qiang Zhang#, Ping Wu#, Feixiang Chen, Yanan Zhao, Yinping Li, Xiaohua He, Céline Huselstein, Qifa Ye, Zan Tong*, Yun Chen*. Brain derived neurotrophic factor and glial cell line-derived neurotrophic factor-transfected bone mesenchymal stem cells for the repair of periphery nerve injury. Frontiers in Bioengineering and Biotechnology. 2020, 8, 874.

[9)]Ping Wu, Ao Xiao, Yanan Zhao, Feixiang Chen, Meifang Ke, Qiang Zhang, Jianwei Zhang, Xiaowen Shi, Xiaohua He, Yun Chen*. An implantable and versatile piezoresistive sensor for the monitoring of human-machine interfacing interactions and dynamical process of nerve repair. Nanoscale. 2019, 11, 21103 – 21118. 

[10] Yanteng Zhao, Yinping Li, Qiaoyue Du, Qiang Zhang, Xianping Lv, Qiankun Yang, Peter R. Chang, Debbie P. Anderson, Meng He*, Yun Chen*. Shape memory histocompatible and biodegradable sponges for subcutaneous defect filling and repair: greatly reducing surgical incision. Journal of Materials Chemistry B. 2019, 7: 5848-5860.

[11] Yanteng Zhao#, Meng He#, Huifang Jin, Lei Zhao, Qiaoyue Du, Hongbing Deng, Weiqun Tian, Yinping Li, Xianping Lv,* Yun Chen*.  Construction of highly biocompatible hydroxyethyl cellulose/soy protein isolate composite sponges for tissue engineering. Chemical Engineering Journal. 2018, 341: 402-413. 

[12] Yanan Zhao, Zijian Wang, Qiang Zhang, Feixiang Chen, Zhiyi Yue, Tiantian Zhang, Hongbing Deng, Céline Huselstein, Debbie P. Anderson, Peter R. Chang, Yinping Li*, Yun Chen*. Accelerated skin wound healing by soy protein isolate–modified hydroxypropyl chitosan composite films. International Journal of Biological Macromolecules. 2018, 118: 1293-1320.

[13] Yanan Zhao, Hongyu Liu, Zijian Wang, Qiang Zhang, Yinping Li, Weiqun Tian, Zan Tong, Yingying Wang, Céline Huselstein, Xiaowen Shi*, Yun Chen*. Electrodeposition to construct mechanically robust chitosan-based multi-channel conduits. Colloids and Surfaces B: Biointerfaces. 2018, 163: 412-418.

[14] Pengkun Zhao, Yanan Zhao, Ling Xiao, Hongbing Deng, Yumin Du, Yun Chen*, Xiaowen Shi*. Electrodeposition to construct free-standing chitosan/layered doublehydroxides hydro-membrane for electrically triggered protein release. Colloids and Surfaces B: Biointerfaces, 2017, 158(10): 474-479.  

[15] Yanteng Zhao#, Meng He#, Lei Zhao, Shiqun Wang, Yinping Li, Li Gan, Mingming Li, Li Xu, Peter R. Chang, Debbie P. Anderson, Yun Chen*. Epichlorohydrin-cross-linked hydroxyethyl cellulose/soy protein isolate composite films as biocompatible and biodegradable implants for tissue engineering. ACS Applied Materials Interfaces. 2016, 8, 2781-2795.  

[16] Li Gan#, Lei Zhao#, Yanteng Zhao, Ke Li, Zan Tong, Li Yi, Xiong Wang, Yinping Li, Weiqun Tian, Xiaohua He, Min Zhao, Yan Li, Yun Chen*. Cellulose/soy protein composite-based nerve guidance conduits with designed microstructure for peripheral nerve regeneration. Journal of Neural Engineering. 2016, 13, 056019(17pp).

[17] Xiaomei Wang, Ling Hu, Chen Li, Li Gan, Meng He, Xiaohua He, Weiqun Tian, Mingming Li, Li Xu, Yinping Li*, Yun Chen*. Improvement in physical and biological properties of chitosan/soy protein films by surface grafted heparin. International Journal of Biological Macromolecules. 2016, 83, 19-29.

[18] Hua Wu, Jiaoyan Liu, Jingjing Wu, Ying Wan*, Yun Chen*. Controlled delivery of platelet-derived growth factor-BB from injectable microsphere/hydrogel composites. Colloids and Surfaces B: Biointerfaces. 2016, 148, 308-316. 

[19] Jun You#, Jinfeng Cao#, Yanteng Zhao, Lina Zhang, Jinping Zhou*, Yun Chen*. Improved mechanical properties and sustained release behavior of cationic cellulose nanocrystals reinforeced cationic cellulose injectable hydrogels. Biomacromolecules 2016, 2838-2849.