刘敏
刘敏

1、职称职务: 讲师OLYMPUS DIGITAL CAMERA

2、学科专业: 免疫学

3、研究方向: 感染免疫、免疫调节                                        

4、联系电话: 

5、Email: lliumin2002@163.com

6、学习经历:

  1995.9-2000.6,滨州医学院,临床医学专业 学士; 

  2000.7-2003.6,武汉大学,基础医学院,免疫学专业,硕士

  2003.7-2006.6,武汉大学,基础医学院,病原生物学专业,硕士

7、主要工作经历与任职 

  2006.7 –2011.3,武汉大学,基础医学院,病原生物学系,讲师

  2011.3-2013.3,美国University of Louisville , 博后

  2013.3 -至今,武汉大学,基础医学院,免疫学系 讲师

8、目前主要科学研究领域和兴趣

  主要研究方向为免疫负性调节细胞在肿瘤、感染中的调控作用及机制。

9、教学情况:

  承担本科生以及研究生《医学免疫学》《损伤及反应》理论和实验教学。

10、近5年代表性论文

  

(1)Liu M, Tong Z, Ding C, Luo F, Wu S, Wu C, Albeituni S, He L, Hu X, Tieri D, Rouchka EC, Hamada M, Takahashi S, Gibb AA, Kloecker G, Zhang HG, Bousamra M 2nd, Hill BG, Zhang X, Yan J. Transcription factor c-Maf is a checkpoint that programs macrophages in lung cancer. J Clin Invest. 2020 Apr 1;130(4):2081-2096.

(2)Liu M, Chen HY, Luo L, Wang Y, Zhang D, Song N, Wang FB, Li Q, Zhang XL, Pan Q. Neutralization of IL-10 produced by B cells promotes protective immunity during persistent HCV infection in humanized mice. Eur J Immunol. 2020 Apr 27.

(3)Ma Y, Deng M, Zhao XQ, Liu M.Alternatively Polarized Macrophages Regulate the Growth and Differentiation of Ependymal Stem Cells through the SIRT2 Pathway. Exp Neurobiol. 2020 Apr 30;29(2):150-163.

(4)Ma Y, Deng M, Liu M. Effect of differently polarized macrophages on proliferation and differentiation of ependymal cells from adult spinal cord. J Neurotrauma. 2019 Aug 1;36(15):2337-2347.

(5)Li S, Liu XY, Pan Q, Wu J, Liu ZH, Wang Y, Liu M, Zhang XL.Hepatitis C Virus-Induced FUT8 Causes 5-FU Drug Resistance in Human Hepatoma Huh7.5.1 Cells. Viruses. 2019 Apr 24;11(4):378.

(6)Zhao R#, Liu M#, Li X, Chen H, Deng J, Huang C, Zhang XL, Pan Q.  A strategy of targeting B10 cell by CD19scFv-IL10R for tumor therapy. Biochem Biophys Res Commun. 2018 Dec 2; 506(4):990-996.

(7)Liu M, Zhao X, Ma Y, Zhou Y, Deng M, Ma Y. Transcription factor c-Maf is essential for IL-10 gene expression in B cells. Scand J Immunol. 2018 Sep;88(3):e12701.

(8)Lv Z#, Liu M#, Shen J, Xiang D, Ma Y, Ji Y. Association of serum interleukin-10, interleukin-17A and transforming growth factor-α levels with human benign and malignant breast diseases. Exp Ther Med. 2018 Jun;15(6):5475-5480.

(9)Liu M, Deng M, Ma Y. Differently polarized macrophages affect the viability and growth of NSPCs by regulating the expression of PACAP. Neuropeptides, 2017(65): 114–119.

(10)Liu M#, Luo F#, Ding C#, Albeituni S, Hu X, Ma Y, Cai Y, McNally L, Sanders MA, Jain D, Kloecker G, Bousamra M, Zhang HG, Higashi RM, Lane AN, Fan TW, Yan J. Dectin-1 Activation by a Natural Product β-Glucan Converts Immunosuppressive Macrophages into an M1-like Phenotype. J Immunol. 2015, 195(10):5055-65.